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Gastroenterologie
a hepatologie

Gastroenterology and Hepatology

Gastroent Hepatol 2020; 74(3): 204–211. doi:10.14735/amgh2020204.

Disconnected pancreatic duct syndrome – a neglected complication of acute pancreatitis

Petr Vaněk1, Přemysl Falt Orcid.org  2,3, Ondřej Urban Orcid.org  4,3

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Summary

Acute pancreatitis is a reversible pancreatic inflammatory process that may be accompanied by local and systemic complications. In a subset of patients with severe acute pancreatitis, necrosis affecting the major pancreatic duct may result in a discontinuity between the left-sided pancreas and duodenum. Such an interruption in the setting of a viable upstream portion of gland parenchyma gives rise to the disconnected pancreatic duct syndrome, which is generally regarded as a dia­gnostically and therapeutically difficult condition. The syndrome is associated with a prolonged disease course and poses a burden on patients’ quality of life and high health care resource utilization. There are currently no universally accepted guidelines for the dia­gnosis and treatment, the syndrome is often neglected and dia­gnosis delayed. The aim of our review article is to raise awareness of this serious complication of acute pancreatitis.

Key words: pancreatitis – acute necrotizing pancreatitis – pancreatic ducts – disconnected pancreatic duct syndrome – walled-off necrosis – pancreatic pseudocyst – pancreatic fistula

Keywords

pancreatitis, pancreatic pseudocyst, walled-off pancreatic necrosis, akutní nekrotizující pankreatitida, syndrom odpojeného pankreatického vývodu, pankreatická fistula

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