Gastroenterologie
a hepatologie

Structure and function of the intestinal epithelial barrier

Pavel Polák ^{Orcid.org  1,2}, Jana Juránková ^Orcid.org  , Petr Husa³

+ Affiliation
¹ LF MU Brno
² Klinika infekčních chorob FN Brno
³ Klinika infekčních chorob LF MU a FN Brno

Summary

In recent years, there has been a revolutionary outbreak of our knowledge about ultra-/structure and function of the intestinal epithelial barrier. During evolution acquisited ability of the macroorganism to dynamically coordinate the interaction with the complexe colonizing microbial ecosystem has been recently shown to be crucial in the health and in the illness-prevention. As acute as chronic pathological conditions, primarilly infectious or non-infectious, may lead to disruption of the intestinal epithelial barrier. The presented overview summarises actual knowledge about structure and function of the intestinal epithelial barrier.

Keywords

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