Gastroenterologie
a hepatologie

Risk of liver fibrosis in patients undergoing surgical treatment of hip trauma

Martin Sedlář¹, Václav Šmíd ^{Orcid.org  2}, Šimon Dostál², Radan Brůha ^{Orcid.org  2}, Petr Dytrych ^{Orcid.org  1}

+ Affiliation
¹ I. chirurgická klinika 1. LF UK a VFN v Praze
² IV. interní klinika – klinika gastroenterologie a hepatologie 1. LF UK a VFN v Praze

Summary

Introduction: Liver fibrosis is a consequence of chronic liver disease and often develops covertly over a long period of time. Fibrosis is also a risk factor for extrahepatic diseases, including frailty. The aim of our study was to determine the risk of liver fibrosis in a group of patients with hip trauma. Methods: Patients with surgical treatment of hip trauma were retrospectively evaluated using non-invasive liver fibrosis indices (NAFLD fibrosis score, FIB-4 and APRI score). The control group consisted of patients with diabetes. Results: A total of 72 patients and 72 controls were evaluated. Using the most appropriate index (FIB-4 adjusted for age), 46% of patients had no risk of liver fibrosis, 43% of patients had moderate or indeterminate risk of fibrosis, and 11% of patients were highly likely to have clinically significant fibrosis. Risk stratification did not differ significantly from the controls. The aetiology of liver fibrosis was most likely due to NAFLD or alcohol abuse. Conclusion: Significant liver fibrosis may be present in 1/10 of patients with hip trauma indicated for surgery. Detection of such patients using non-invasive indices is very simple and should be used for screening in common practice.

Keywords

fibrosis, non-alcoholic fatty liver disease, frailty, hip trauma

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