Recommendation for Vaccinations in Patients with Crohn
Jiří Stehlík Orcid.org 1, Karel Mareš Orcid.org 2, Milan Lukáš Orcid.org 3, Martin Bortlík Orcid.org 3,4,5, Dana Ďuricová Orcid.org 3
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Summary
Summary:
Patients with Crohn's disease and ulcerative colitis on immunosuppressive or biological therapy are exposed to a significantly higher risk of infectious complications. Therefore, these patients require systematic and complex precautions which are focused on the early detection and target treatment of these potentially serious complications. Vaccination at the time of diagnosis of inflammatory bowel disease or before initiating the biological and/or immunosuppressive therapy has become extraordinarily important. From the clinical point of view, the vaccinations against virus hepatitis B, human papilomavirus, varicella zoster infection and pneumococcal infection are the most important. The life vaccine application is allowed 3 months after biological or immunosuppressive therapy is terminated. Treatment with immunosuppressants and biological preparations is strongly recommended not to begin earlier than 3 weeks after life vaccine application. The present recommendations are based on the consensus of theCzech IBDWorking Group and the ECCO Statement.
Keywords
Crohn’s disease, biological therapy, inflammatory bowel disease, immunosuppression, vaccination, ulcerative colitisTo read this article in full, please register for free on this website.
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