Anonymous User
Login / Registration

a hepatologie

Gastroenterology and Hepatology

Gastroent Hepatol 2013; 67(2): 154-161.

Health status and pancreatic cancer

Helena Kollárová  , Katerina Azeem  , Hana Tomášková  1, Vlastimil Procházka  2, Arnošt Martínek  3,4, Olga Shonová  5, Jarmila Ševčíková  6, Dagmar Horáková  , Vladimír Janout  

+ Affiliation


Introduction: The Czech Republic ranks among the countries with high incidence and mortality of pancreatic cancer.

Method: The hospital based case-control study included a total of 529 people (309 pancreatic cancer cases and 220 controls). People in the study came from Olomouc, Ostrava, and Ceske Budějovice (Czech Republic). The relationship between health status (diabetes mellitus, chronic pancreatitis, cholelithiasis), use of medication (aspirin and other anti-inflammatory drugs), the family history (cancer in first-degree relatives), and cancer of the pancreas was studied.

Results: A positive statistically significant association was found in diabetes mellitus (OR 1.84, 95% Cl 1.12-3.03) and pancreatitis (OR 4.10, 95% Cl 1.43-11.81). A statistically significant inverse association was found in the use of aspirin (OR 0.33, 95% Cl 0.17-0.62) and anti-inflammatory drugs (OR 0.28, 95% Cl 0.12-0.65). No association between family history of cancer in first-degree relatives and pancreatic cancer was found.

Conclusion: Because no specific prevention of pancreatic cancer in the form of an effective screening program exists, it is necessary to pay attention to the factors associated with the disease, such as pancreatitis, diabetes mellitus, and metabolic syndrome, for early detection of pancreatic cancer.


pancreatic carcinoma

To read this article in full, please register for free on this website.

Benefits for subscribers

Benefits for logged users

Credited self-teaching test