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a hepatologie

Gastroenterology and Hepatology

Gastroent Hepatol 2020; 74(3): 228–232. doi:10.14735/amgh2020228.

Eosinophilic esophagitis – current overview of dia­gnostic and treatment modalities

Ivana Mikoviny Kajzrlíková1, Petr Vítek2,3

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Eosinophilic esophagitis is immune-mediated inflammatory condition of the esophagus. It is a chronic disease with progressive esophageal remodeling. Eosinophilic esophagitis is characterized by symptoms of esophageal dysfunction and eosinophilic infiltration of the esophageal mucosa in the absence of secondary causes of eosinophilia. The management of eosinophilic esophagitis includes proton pump inhibitors, topical glucocorticoids and dietary interventions. Maintenance therapy should be considered for all patients. Endoscopic interventions include pneumatic dilation to treat strictures in symptomatic patients and extraction of impacted food bolus.

Key words: eosinophilic esophagitis – progression – corticoid – diet – proton pump inhibitors – dilation


proton pump inhibitors, diet, progrese nemoci, kortikoidy

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