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a hepatologie

Gastroenterology and Hepatology

Gastroent Hepatol 2023; 77(1): 52–56. doi: 10.48095/ccgh202352.

Autoimmune hepatitis after vaccination against COVID-19

Veronika Pítová1, Jan Šperl  1, Pavel Taimr  1, Ondřej Fabián2, Tomáš Miřejovský3, Libor Janoušek  4, Jaroslav Chlupáč5,6, Julius Špičák  1, Soňa Fraňková  1

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In this case report, we present a 61-year-old patient admitted to the hospital because of tiredness and jaundice less than three weeks after vaccination against SARS-CoV-2 with the first dose of the Comirnaty vaccine (Pfizer/BioNTech). Based on the patient’s medical history, laboratory data, imaging methods and liver bio­psy, we dia­gnosed autoimmune hepatitis. The patient developed acute liver failure, and his liver function did not improve after corticosteroid administration. Therefore, the patient was enrolled in the waiting list and underwent a successful orthotopic liver transplantation.


autoimunitní hepatitida, COVID-19, vaccination

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