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Gastroenterology and Hepatology

Gastroent Hepatol 2020; 74(4): 339–349. doi:10.14735/amgh2020339.

Acute kidney injury in gastroenterology

Naděžda Petejová1,2, Arnošt Martínek1,2, Josef Zadražil, Vladimír Teplan3,4,5

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Acute kidney injury (AKI) is a common and mostly severe clinical syndrome associated with worsening morbidity and mortality of patients in many fields of medicine, including gastroenterological diseases.
Many of gastroenterological disorders are associated with acute kidney injury (AKI) or with chronic nephropathies. The pathophysiology of AKI in gastroenterology is mostly multifactorial and the influence of these factors on histopathological findings in renal tissue may be considerable.
Appropriate AKI diagnosis and disease severity with possibility of decrease progression of AKI to chronic nephropathy. Necessary is also an adequate therapy of primary gastroenterological disease.
Early diagnosis of secondary AKI and initiation of adequate preventive and therapeutic measures can improve patient‘s outcome and decrease a progression to chronic nephropathy.

Key words: acute kidney injury – tubulointerstitial nephritis – glomerulonephritis – oxalate nephropathy


glomerulonefritida, acute kidney injury, tubulointersticiální nefritida, oxalátová nefropatie

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