Current opinion on the therapy of perianal fistulas in patients with Crohn's disease

Abstract

Perianal fistulas affect more than one third of patients suffering from Crohn's disease. They represent severe phenotype of the disease and substantially decrease the quality of life in affected patients. Therapy requires a complex approach with combination and appropriate coordination of medical treatment and surgical techniques. Using the current medicines, especially biologies, as well as propper surgery, we can achieve the long-term healing in more than 2/3 of patients with perianal Crohn's disease.