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Gastroenterologie
a hepatologie

Gastroenterology and Hepatology

Gastroent Hepatol 2015; 69(6): 531–535. doi:10.14735/amgh2015531.

Exclusive enteral nutrition – first-line therapy of Crohn’s disease in children

Eva Karásková1

+ Affiliation

Summary

Inflammatory bowel diseases include Crohn‘s disease and ulcerative colitis. Up to 20% of patients with Crohn’s disease are diagnosed before the age of 18 years. The onset of the disease in childhood is often accompanied by growth retardation and impaired bone metabolism. The therapeutic approach differs in certain aspects from the treatment of adult patients. Particularly, exclusive enteral nutrition is recommended as first-line therapy to induce remission in children with newly diagnosed Crohn’s disease. Over recent years this therapy has often replaced corticosteroids. According to available studies, this  treatment induces endoscopic remission better than corticosteroids, while improving bone metabolism, growth and nutritional status. Exclusive enteral nutrition is generally well tolerated and with proper administration its complications and side effects are minimal.

Keywords

Crohn’s disease, child, enteral nutrition

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