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a hepatologie

Gastroenterology and Hepatology

Gastroent Hepatol 2019; 73(2): 143–148. doi:10.14735/amgh2019143.

Ectopic pancreas as a cause of upper gastrointestinal bleeding

Michal Vacík1, Filip Shon2, Miroslav Řežábek3

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Differentiated ectopic pancreatic tissue can develop anywhere in the gastrointestinal tract (GIT) and is most frequently found in the gastric or duodenal wall. Nowadays a development of ectopic pancreas stay unclear. The incidence of an ectopic pancreas is 0.55–13.70%, and such tissue is found more frequently in males than in females. Most ectopic pancreases are histologically categorized as type 1 according to Heinrich’s classification and contain all pancreatic components (acini, ducts, and endocrine cells). The majority of cases are asymptomatic; however, a large ectopic pancreas can cause various symptoms. Ectopic pancreatic tissue rarely causes bleeding. Here, we present two case reports. The first case was a middle-aged woman who developed anemia due to ectopic pancreatic tissue in the gastric wall. The second case exhibited acute bleeding due to a subpapillary lesion in the duodenum. Differential diagnosis can be difficult. Surgery and histological examination of the resected GIT led to a definitive diagnosis in both cases.


surgery, choristoma, ectopic tissue, endoscopy, gastrointestinal tract, bleeding, pancreas

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