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Gastroenterologie
a hepatologie

Gastroenterology and Hepatology

Gastroent Hepatol 2019; 73(6): 496–500. doi:10.14735/amgh2019496.

Anti-TNF alpha-induced immune-mediated skin adverse reactions resolved by switching to ustekinumab

Karolína Vorčáková1, Marta Horáková2, Juraj Péč1

+ Affiliation

Summary

Immune-mediated adverse reactions are a new group of conditions that develop during anti-TNF-alpha treatment. Their etiopathogenesis remains unclear. This study describes three forms of immune-mediated adverse reactions of the skin that were diagnosed correctly. Some types of immune-mediated adverse reactions, such as palmoplantar pustular psoriasis, may persist for a long time after switching biologic agents.

Keywords

anti-TNF-alpha, cutaneous adverse effects, ustekinumab

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Literature

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