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Gastroenterologie
a hepatologie

Gastroenterology and Hepatology

Gastroent Hepatol 2018; 72(3): 225–230. doi:10.14735/amgh2018225.

Brunner’s gland adenoma – a rare cause of gastrointestinal bleeding

Martin Kliment Orcid.org  1

+ Affiliation

Summary

Brunner’s gland adenomas are rare benign tumors of the duodenum, which are often diagnosed incidentally during esophagogastroduodenoscopy or upper gastrointestinal series. The lesions are most commonly asymptomatic, but a minority of patients may present with symptoms of duodenal obstruction or hemorrhage secondary to ulceration. Histologically, a Brunner’s gland adenoma consists of components of Brunner’s gland cells, as well as glandular, adipose and muscle cells. We report a case of a 53-year-old woman with a Brunner’s gland adenoma with a size of 3.5 cm, causing an upper gastrointestinal bleeding. Endosonography revealed a highly vascularized duodenal tumor arising from the submucosa. After histological examination of an endosonographically guided fine needle aspiration biopsy revealed a Brunner’s gland adenoma, the adenoma was successfully removed using a polypectomy snare and an endoloop. We also present a literature review, including other therapy options.

Keywords

Brunner’s gland, endoscopic polypectomy, gastrointestinal bleeding, duodenal polyp

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